That is a link to recent B-d-mannuronic acid research on its use to treat RA patients.
Mannuronic acid is:
“Uronic acid derived from the oxidation of mannose; a component of alginic acid.”
This research seems promising. However, I could not find anywhere on the Internet if this NSAID is available for the treatment of AS and RA in pill form, yet. Meaning, is M2000 on the market? I could not find it in the drugs.com online database.
It (mannuronic acid) is a byproduct of Alginate (alginic acid), and has something to do with algae, seaweed, and that is something I am allergic to. However, it may be so processed by the time it has entered pill-form, that the allergic properties are very minor or non-existent, as this research seems to say.
“Alginates are refined from brown seaweeds. A wide variety of brown seaweeds of the phylum Phaeophyceae are harvested throughout the world to be converted into the raw material commonly known as sodium alginate. Sodium alginate has a wide use across a wide variety of industries including food, textile printing and pharmaceutical.”
Source: Wikipedia, https://en.m.wikipedia.org/wiki/Alginic_acid
I also could not find which Big-Pharma company owns the patent on this. Someone always owns the patent.
It seems that this M2000 has no, or little gastritis effects, which is a big plus.
Maybe M2000 will be (more widely) available soon for the treatment of RA and AS.